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4F-MPH

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Description

4F-MPH

4-Fluoromethylphenidate (commonly known as 4F-MPH) is a novel synthetic stimulant of the substituted phenethylamine and piperidine classes that produces long-lasting euphoriant, and stimulating effects associated with monoamine reuptake inhibitors when adminstered. It is a closely related structural analog of the commonly prescribed ADHD drug methylphenidate (known by the brand-names Ritalin and Focalin).

The two substances are believed to have very similar pharmacological mechanisms but have been reported to display distinctive subjective effects, with 4F-MPH being considered significantly more euphoric and recreational. Anecdotal reports suggest that it is considerably more potent with fewer uncomfortable side effects such as anxiety, muscle spasms and compulsive redosing.[1] This perhaps owes to the fact that it has been shown to act as a higher efficiency dopamine reuptake inhibitor than the parent compound methylphenidate.

4F-MPH has an extremely short history of recreational use and has yet to be documented being sold on the streets. It was initially developed as a replacement for ethylphenidate which became illegal in the United Kingdom on April 2015 following a temporary blanket ban. Shortly after, it recently became made available for sale on the online gray market as a research chemical for global distribution.

Due to its potent, long-lasting stimulant effect, likely habit-forming properties as well as unknown toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance.

 

 

 

4-Fluoromethylphenidate (commonly known as 4F-MPH) is a novel synthetic stimulant of the substituted phenethylamine and piperidine classes that produces long-lasting euphoriant, and stimulating effects associated with monoamine reuptake inhibitors when adminstered. It is a closely related structural analog of the commonly prescribed ADHD drug methylphenidate (known by the brand-names Ritalin and Focalin).

The two substances are believed to have very similar pharmacological mechanisms but have been reported to display distinctive subjective effects, with 4F-MPH being considered significantly more euphoric and recreational. Anecdotal reports suggest that it is considerably more potent with fewer uncomfortable side effects such as anxiety, muscle spasms and compulsive redosing.[1] This perhaps owes to the fact that it has been shown to act as a higher efficiency dopamine reuptake inhibitor than the parent compound methylphenidate.

4F-MPH has an extremely short history of recreational use and has yet to be documented being sold on the streets. It was initially developed as a replacement for ethylphenidate which became illegal in the United Kingdom on April 2015 following a temporary blanket ban. Shortly after, it recently became made available for sale on the online gray market as a research chemical for global distribution.

Due to its potent, long-lasting stimulant effect, likely habit-forming properties as well as unknown toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance.

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